Specific conditions commonly affecting patients being evaluated for transplantation can sometimes make a person ineligible, or too sick, to undergo surgery. During this session, we will examine specific challenges affecting transplant eligibility, with a special focus on evolving practices and standard exclusion criteria including BMI, substance use, and social support. Should certain criteria remain absolute contraindications, or are there alternative testing methods or criteria that could better assess patient suitability? Join us to learn about innovative strategies adopted by transplant centers to enhance support systems and effectively navigate these challenges.