As the demand for organ transplants continues to grow, so does the need for seamless coordination between OPOs and Transplant Centers. This session will examine the complex, and often conflicting, objectives that drive OPOs and Transplant Centers, with a focus on how performance metrics, regulatory mandates, and ethical frameworks influence their collaboration. Through thoughtful discussion and real-world insights, the professional community will gain a deeper understanding of the systemic pressures each stakeholder faces and explore strategies to foster greater alignment across the organ donation and transplantation continuum.