The lymphocytotoxic crossmatch test detects antibodies in the recipient that react with donor HLA antigens prior to transplantation. Lymphocytotoxic crossmatch tests are used primarily for transplant candidates to assess the suitability of a potential donor. A positive lymphocytotoxic crossmatch identifies antibodies responsible for hyperacute rejection of kidney grafts and is therefore a clear contraindication to transplantation. (Organdonor.gov April 2020)
Glossary Term