George Mazariegos

Professor of Surgery, Jamie Lee Curtis Endowed Chair in Transplantation Surgery; Director, Pediatric Transplant Surgery
University of Pittsburgh - Children’s Hospital of Pittsburgh
George Mazariegos

Brief Bio

George Mazariegos, MD, FACS is Chief of Pediatric Transplantation at UPMC Children’s Hospital of Pittsburgh, Hillman Center for Pediatric Transplantation and at the Thomas E. Starzl Transplantation Institute. He is a professor at the University of Pittsburgh in the departments of Surgery, Anesthesiology and Critical Care Medicine and holds the Jamie Lee Curtis Chair in Pediatric Transplantation Surgery.

Dr. Mazariegos’ research has focused on refining immunosuppression therapy to improve transplant outcomes and quality of life, optimizing utility of intestine and liver graft donors to reduce wait list mortality and improving long term outcomes in pediatric liver and intestine transplantation. Dr. Mazariegos is co-founder and Chair of the Executive Steering Committee of the Starzl Network for Excellence in Pediatric Transplantation, a Learning Health System designed to transform transplantation by combining transparency, best practices, and patient reported outcomes with innovative technology.

Alliance Presentations

Healthy Liver. Human Hands Holding Liver Symbol On White Backgro

Preventing Pediatric Liver Waitlist Deaths: A Call to Action!

Wednesday, September 27, 2023, at 3:00pm

The Alliance Conversation Series brings you cost-free, fast-paced collaborative opportunities that highlight successful donation and transplantation practices across the country. Through shared insight, multidisciplinary experts identify solutions to critical challenges affecting the community of practice and actively share them for open discussion and broader knowledge of effective practices.

The sessions encourage real-time feedback and participation from viewers.

Overview: Children, especially those under 5 years of age, have the highest death rate on the transplant waiting list compared to any other age range. Countries like UK and Australia have been able to almost eliminate waitlist death of children through a combination of centralization of liver transplant services and an intention to split policy. In the US, despite the organ donation rates per million population exceeding that of the UK or Australia, deaths on the waiting list remains high. Pediatric liver transplantation waitlist mortality is a solvable problem, with the solution likely reachable by multiple pathways. An analysis led by University of Pittsburgh and collaborators from the Starzl Network for Excellence in Pediatric Transplantation ( suggests that greater use of partial liver transplants, either from a living donor or by splitting a deceased donor’s liver for two recipients, could save many of these young lives.

In this session, we will explore successful Australian pediatric liver transplant policy and practices and discuss opportunities for improvement in the US to achieving zero wait list mortality with ideal outcomes

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